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an erection that won't go away (priapism). When you have an erection that lasts much more than four hours, get healthcare enable right away. If It isn't taken care of instantly, priapism can completely hurt your penis.Il tadalafil può inibire debolmente anche la fosfodiesterasi di tipo 6 (PDE6; 700 volte meno potente sulla PDE6 rispetto alla PDE5)